Frequently Asked Questions

Exosomes are tiny vesicles (30–150 nm) secreted by cells. They carry signals for intercellular communication, including messages related to skin regeneration and repair. CELLshot products feature a high concentration of active ingredients inspired by exosome biology.

CELLshot is a skincare brand built on the tiptop technology platform. tiptop is a regenerative science platform rooted in Nobel laureate laboratory research, translating advanced regenerative medicine into everyday skincare. Explore the full platform at tiptop.ruben86cn1.cloud.

A freeze-dried (lyophilized) serum preserves active ingredients in a dry, solid state. It is mixed with a solvent immediately before use, maintaining maximal potency. Compared to liquid serums, it retains over 95% activity even after long-term storage.

Lyophilized active ingredients and solvent are stored in separate chambers and mixed right before application. This prevents oxidation and degradation, ensuring you always receive a fresh, fully potent formula.

The exosome-derived ingredients in CELLshot products achieve over 99.9% purity. Our proprietary ExosomeBeta purification technology ensures high purity and high bioactivity.

Conventional serums are stored in liquid form for extended periods, whereas CELLshot freeze-dried serums are activated immediately before use. This minimizes ingredient degradation and maximizes efficacy.

Yes, this product is ideal for post-procedure care after laser treatments or chemical peels. After a procedure, the skin barrier is temporarily compromised, allowing for enhanced absorption of potent active ingredients. Please follow your physician's guidance on the appropriate timing for use.

All our products are dermatologist-tested. However, individual results may vary. For first-time use, we recommend performing a patch test on the inner arm to confirm no adverse reaction before applying to the face.

CELLshot is suitable for all skin types — dry, combination, and oily — particularly for those interested in age-management skincare. It is ideal for individuals concerned about skin firmness and elasticity, or those seeking specialized post-procedure care.

CELLshot is built on the tiptop technology platform and employs freeze-drying with dual-chamber technology. Its raw materials are registered with Japan JCIA and US INCI, and manufactured on GMP-certified production lines. Explore the full scientific platform at tiptop.ruben86cn1.cloud.

Yes. Our technology foundation is backed by 36 peer-reviewed papers published in top-tier journals including Nature (2015) and Science Translational Medicine (2024). For details, visit tiptop science platform. A human clinical trial (Report HZ-F-2500025) demonstrated a 19.40% reduction in nasolabial fold volume and a 34.47% improvement in skin elasticity after 28 days.

Nature 2015 (DOI: 10.1038/nature13903), Science Translational Medicine 2024 (DOI: 10.1126/scitranslmed.adi3360). For the full list, please visit the /evidence page.

CELLshot is a cosmetic product, not a pharmaceutical. In an SGS patch test with 33 sensitive-skin subjects, the majority showed no skin irritation. If redness, itching, or any unusual reaction occurs, discontinue use and consult a physician.

Before opening, store at room temperature away from direct sunlight. After opening, keep in a cool, dark place and use as soon as possible.

Currently, CELLshot is available exclusively through our official website (https://cellshot.ruben86cn1.cloud). Authorized retail partners will be announced as we expand.

Currently, we only ship within Japan. International shipping is in preparation. For overseas inquiries, please contact b2b@cellshot.ruben86cn1.cloud.

Unopened and unused items may be returned within 30 days of delivery. After verifying the product condition, we will issue a full refund.

Yes. Please indicate your request in the order notes. Complimentary gift wrapping is available.

CELLshot is for women who understand cutting-edge regenerative science and seek cell-level skin reconstruction rather than superficial age management. They value evidence-based efficacy and choose products based on scientific depth rather than price — a brand for the top 1% of discerning women worldwide.

No, CELLshot is a cosmetic product. It is not a pharmaceutical or medical device and is not intended to treat, diagnose, or prevent any disease. It is not designed for injection or invasive procedures.

CELLshot products do not contain stem cells themselves. They are cosmetics formulated with exosome-inspired ingredients. Unlike stem cell therapy or regenerative medicine, CELLshot is intended exclusively as a topical skincare product.

Orders are typically shipped within 2–3 business days. Deliveries to Hokkaido and Okinawa may take an additional 5–7 business days.

Yes, all products are dermatologist-tested. However, as individual reactions vary, we recommend a patch test before first use.

Currently, we only ship within Japan. International shipping will be available in the future.

Yes. You earn points with every purchase (1 JPY = 1 point), redeemable on future orders.

Full ingredient lists are available on each product page. Most of our products are free of artificial fragrances, colorants, and alcohol.